{"product_id":"principelle-if-medical-grade-honey-based-bio-active-wound-care-formulation-8cm-x-20cm","title":"Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10","description":"\u003cdiv id=\"ai-summary\" style=\"background:#f0f6ff;border-left:4px solid #0057a8;padding:14px 18px;margin-bottom:20px;font-family:Arial,sans-serif;font-size:14px;line-height:1.6;\"\u003e\n\u003cstrong\u003eAI Summary:\u003c\/strong\u003e Principelle If Medical Grade Honey Bioactive Wound Care Formulation (8 cm × 20 cm, Box of 10) is a non-adhesive antimicrobial wound contact layer impregnated with ≥18% w\/w standardised medical-grade Leptospermum (manuka-type) honey, providing a minimum inhibitory concentration effective against MRSA, MSSA, Pseudomonas aeruginosa, and extended-spectrum beta-lactamase (ESBL) producing organisms. The bioactive honey matrix maintains a moist wound environment, facilitates autolytic debridement, and generates hydrogen peroxide at wound pH through glucose-oxidase activity. Indicated for chronic wounds, surgical wounds, burns, and ulcers. Complies with ISO 10993 (biocompatibility), ISO 13485:2016 quality management. HSA-registered Class B medical device, Singapore.\n\u003c\/div\u003e\n\n\u003cp\u003e\u003cstrong\u003ePrincipelle If Medical Grade Honey Bioactive Wound Care Formulation\u003c\/strong\u003e (8 cm × 20 cm, Box of 10) delivers clinically validated antimicrobial activity through standardised Leptospermum honey chemistry, offering broad-spectrum bacterial suppression without antibiotic resistance risk — critical for biofilm-forming organisms in chronic wound management.\u003c\/p\u003e\n\n\u003ch2\u003eTechnical Specifications\u003c\/h2\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:14px;margin-bottom:20px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background:#0057a8;color:#ffffff;\"\u003e\n\u003cth style=\"padding:9px 12px;text-align:left;width:42%;\"\u003eParameter\u003c\/th\u003e\n\u003cth style=\"padding:9px 12px;text-align:left;\"\u003eSpecification\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eHoney Concentration\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003e≥18% w\/w standardised medical-grade Leptospermum honey\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eDressing Dimensions\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003e8 cm × 20 cm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003ePack Size\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eBox of 10 dressings\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eDressing Type\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eNon-adhesive antimicrobial wound contact layer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eAntimicrobial Spectrum\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eMRSA, MSSA, Pseudomonas aeruginosa, ESBL-producing Enterobacteriaceae\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eMechanism\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eGlucose-oxidase H₂O₂ generation; osmotic bacteriostasis; low pH environment\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eWound Environment\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eMoist wound healing; facilitates autolytic debridement\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eIndications\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eChronic wounds, leg ulcers, pressure injuries, surgical wounds, partial-thickness burns, infected wounds\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eSterility\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eSterile; single-use; gamma-irradiated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eBiocompatibility\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eISO 10993 tested; latex-free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eQuality Management\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eISO 13485:2016\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eSingapore Registration\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eHSA-registered Class B medical device\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eClinical Q\u0026amp;A\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How does the Principelle If honey formulation achieve antimicrobial activity without antibiotics?\u003c\/strong\u003e\u003cbr\u003e\nA: Three independent mechanisms act synergistically: (1) glucose-oxidase enzyme catalyses slow H₂O₂ generation at the wound surface, disrupting bacterial cell membranes; (2) high osmolarity draws fluid from bacterial cells via osmotic gradient; (3) low pH (3.2–4.5) inhibits bacterial metalloprotease activity and biofilm formation. The multi-modal mechanism prevents the development of resistance that characterises antibiotic monotherapy.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: What is the recommended dressing change frequency for chronic wound management?\u003c\/strong\u003e\u003cbr\u003e\nA: Change frequency is determined by exudate volume. For heavily exuding wounds, daily changes are appropriate as honey dilution by exudate reduces antimicrobial concentration. For moderate exudate, every 2–3 days is typical. Wound assessment should include evaluation of surrounding skin maceration, which indicates excessive moisture requiring secondary dressing adjustment.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: Is the 8 cm × 20 cm format appropriate for leg ulcers and pressure injuries?\u003c\/strong\u003e\u003cbr\u003e\nA: Yes. The elongated 8 × 20 cm format is specifically suited for venous leg ulcers along the gaiter area, sacral pressure injuries, and post-surgical wound dehiscence sites where wound shape is irregular or linear. Dressings can be cut to size without compromising sterility at the cut edge, provided scissors are sterile. A secondary absorbent dressing is required to manage exudate and secure placement.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: Can Principelle If honey dressings be used on infected wounds with biofilm?\u003c\/strong\u003e\u003cbr\u003e\nA: Clinical evidence supports medical-grade honey as an adjunctive biofilm management strategy. Honey's osmotic and acidic environment disrupts the extracellular polymeric substance (EPS) matrix of Pseudomonas and Staphylococcal biofilms, enhancing susceptibility to concurrent systemic antibiotics. Debridement prior to application is recommended to maximise honey-tissue contact in heavily biofilmed wounds.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: What regulatory approvals and quality standards apply to this product?\u003c\/strong\u003e\u003cbr\u003e\nA: Principelle If is manufactured under ISO 13485:2016 quality management and has passed ISO 10993 biocompatibility testing (cytotoxicity, sensitisation, systemic toxicity). It is registered with Singapore's Health Sciences Authority (HSA) as a Class B medical device, confirming conformity with applicable essential principles for wound care dressings under the Health Products Act.\u003c\/p\u003e\n\n\u003ch2\u003eRegulatory \u0026amp; Standards References\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eISO 13485:2016\u003c\/strong\u003e — Medical devices quality management system; Principelle If manufacturing certification\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eISO 10993\u003c\/strong\u003e — Biological evaluation of medical devices; cytotoxicity and sensitisation testing completed\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHSA Singapore\u003c\/strong\u003e — Class B medical device registration under the Health Products Act (wound care dressing classification)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNICE Evidence Review\u003c\/strong\u003e — Medical-grade honey wound dressings; supports use in infected chronic wounds refractory to standard antimicrobials\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEWMA Position Document\u003c\/strong\u003e — European Wound Management Association guidance on antimicrobial dressings for infected wounds\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"Product\",\n  \"name\": \"Principelle If Medical Grade Honey Bioactive Wound Care Formulation 8cm x 20cm Box of 10\",\n  \"description\": \"Medical-grade Leptospermum honey wound contact dressing (8×20cm, box 10). ≥18% w\/w honey, broad-spectrum antimicrobial including MRSA. ISO 10993, ISO 13485:2016. HSA-registered Class B medical device. Singapore.\",\n  \"brand\": { \"@type\": \"Brand\", \"name\": \"Principelle\" },\n  \"offers\": {\n    \"@type\": \"Offer\",\n    \"priceCurrency\": \"SGD\",\n    \"price\": \"400.00\",\n    \"availability\": \"https:\/\/schema.org\/InStock\",\n    \"seller\": { \"@type\": \"Organization\", \"name\": \"Essential Medical International Supplies Pte Ltd\", \"url\": \"https:\/\/www.emis.asia\" }\n  },\n  \"additionalProperty\": [\n    { \"@type\": \"PropertyValue\", \"name\": \"Honey Concentration\", \"value\": \"≥18% w\/w Leptospermum\" },\n    { \"@type\": \"PropertyValue\", \"name\": \"Dimensions\", \"value\": \"8cm × 20cm\" },\n    { \"@type\": \"PropertyValue\", \"name\": \"Regulatory\", \"value\": \"ISO 10993, ISO 13485:2016, HSA Class B\" }\n  ]\n}\n\u003c\/script\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 by Principelle is a advanced wound dressing used for wound management. It is designed to support moist wound healing, manage exudate, and protect the wound bed from contamination. It is commonly used in Singapore hospitals and home care settings for chronic wounds, post-surgical wounds, and ulcers. Always follow the guidance of your wound care nurse or doctor when selecting a dressing.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How often should Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 be changed?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 should generally be changed every 1–7 days depending on wound type and exudate. However, frequency should always be guided by your wound care nurse or clinician based on wound size, exudate level, and signs of infection. Do not leave any dressing in place if it becomes saturated, dislodged, or if the wound shows signs of infection such as increased redness, warmth, or discharge.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 available without prescription in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes, Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 is available for purchase from EMIS+ (emis.asia) without a prescription for general wound care use. For complex or chronic wounds, we strongly recommend consulting a wound care nurse, GP, or specialist at a Singapore hospital such as SGH, NUH, TTSH, or CGH before selecting a dressing. EMIS+ nurses can also provide product guidance — contact us at emis.asia\/pages\/contact.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Principelle If Medical Grade Honey Based Bio Active Wound Care Formulation 8cm x 20cm Box of 10 is available from EMIS+ at emis.asia, Singapore's nurse-led medical supply store. We offer fast island-wide delivery, competitive pricing, and bulk ordering for healthcare facilities and home care users. Visit emis.asia or contact our team for assistance.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Principelle","offers":[{"title":"Default Title","offer_id":42741428879438,"sku":null,"price":400.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/Principelle_IF_5cm_x_6cm_6.png?v=1753974829","url":"https:\/\/th.emis.asia\/products\/principelle-if-medical-grade-honey-based-bio-active-wound-care-formulation-8cm-x-20cm","provider":"EMIS+","version":"1.0","type":"link"}