{"title":"Pendulum","description":"\u003cdiv class=\"col-aeo\"\u003e\n\u003cp\u003e\u003cstrong\u003ePendulum is a next-generation probiotics brand founded by PhD scientists, best known for pioneering live Akkermansia muciniphila — a keystone gut strain.\u003c\/strong\u003e EMIS+ supplies Pendulum probiotics in Singapore.\u003c\/p\u003e\n\u003ch2\u003eThe Pendulum range\u003c\/h2\u003e\n\u003cp\u003ePendulum's line includes single-strain \u003ca href=\"\/en\/collections\/akkermansia\"\u003eAkkermansia\u003c\/a\u003e (to support the gut lining), Metabolic Daily (a multi-strain formula for metabolism, digestion and energy), and Glucose Control, a probiotic studied for supporting healthy blood-sugar management. These are health supplements and not a substitute for medical treatment — if you manage diabetes or a medical condition, speak with your doctor before use.\u003c\/p\u003e\n\u003c\/div\u003e","products":[{"product_id":"akkermansia-muciniphila-capsule-30s","title":"Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore","description":"\u003ch2\u003eAkkermansia Muciniphila Probiotic Capsules — Advanced Gut Health Support\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eAkkermansia muciniphila\u003c\/strong\u003e is one of the most researched beneficial bacteria in the human gut microbiome. EMIS+ stocks authenticated Akkermansia Muciniphila capsules for patients and health-conscious individuals in Singapore seeking advanced gut health support, metabolic wellness, and intestinal barrier integrity.\u003c\/p\u003e\n\n\u003ch3\u003eWhy Akkermansia Muciniphila?\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e🦠 \u003cstrong\u003eNext-generation probiotic\u003c\/strong\u003e — Akkermansia muciniphila is a mucus-layer bacterium that plays a critical role in gut barrier function, unlike conventional Lactobacillus or Bifidobacterium probiotics\u003c\/li\u003e\n\u003cli\u003e🔬 \u003cstrong\u003eClinically researched\u003c\/strong\u003e — extensively studied for its role in metabolic health, weight management, type 2 diabetes management, and inflammatory bowel conditions\u003c\/li\u003e\n\u003cli\u003e🛡️ \u003cstrong\u003eGut barrier integrity\u003c\/strong\u003e — helps strengthen the intestinal mucous layer, reducing intestinal permeability (\"leaky gut\")\u003c\/li\u003e\n\u003cli\u003e⚖️ \u003cstrong\u003eMetabolic health\u003c\/strong\u003e — research links higher Akkermansia levels to healthier BMI and improved glucose metabolism\u003c\/li\u003e\n\u003cli\u003e❤️ \u003cstrong\u003eAnti-inflammatory effects\u003c\/strong\u003e — supports reduction of systemic low-grade inflammation associated with metabolic syndrome\u003c\/li\u003e\n\u003cli\u003e💊 \u003cstrong\u003e30 capsules per bottle\u003c\/strong\u003e — one month's supply\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWho Benefits from Akkermansia Supplementation?\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eIndividuals with gut permeability (\"leaky gut\") concerns\u003c\/li\u003e\n\u003cli\u003ePatients with metabolic syndrome, prediabetes, or type 2 diabetes (complement to medical management)\u003c\/li\u003e\n\u003cli\u003eThose with inflammatory bowel conditions seeking microbiome support\u003c\/li\u003e\n\u003cli\u003eAnyone looking to diversify and strengthen their gut microbiome beyond conventional probiotics\u003c\/li\u003e\n\u003cli\u003eIndividuals with low fibre intake or diet-related microbiome disruption\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eDosage \u0026amp; How to Use\u003c\/h3\u003e\n\u003cp\u003eTake as directed on the product label, typically 1 capsule daily with or without food. For best results, pair with a diet rich in prebiotic fibres (polyphenol-rich foods, vegetables, legumes) which support Akkermansia colonisation. Consult your healthcare provider before starting any new supplement, particularly if you have a medical condition or are on medication.\u003c\/p\u003e\n\n\u003ch3\u003eStorage\u003c\/h3\u003e\n\u003cp\u003eStore in a cool, dry place away from direct sunlight. Refrigeration may extend shelf life. Do not use if the seal is broken.\u003c\/p\u003e\n\n\u003ch3\u003eWhy Buy from EMIS+?\u003c\/h3\u003e\n\u003cp\u003eEMIS+ is Singapore's nurse-led medical supply store. We source authentic Akkermansia supplements from verified distributors. Our clinical team is available for free consultation on gut health supplementation and product selection.\u003c\/p\u003e\n\n\u003cp\u003e📦 \u003cstrong\u003eFast islandwide delivery\u003c\/strong\u003e across Singapore. Regional shipping across Asia available.\u003c\/p\u003e\n\u003cp\u003e💬 \u003cstrong\u003eFree nurse consultation\u003c\/strong\u003e — our team can advise on whether Akkermansia is right for your health goals.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eThis product is a food supplement. It is not intended to diagnose, treat, cure, or prevent any disease. Always consult a healthcare professional before starting a new supplement regime.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003chr\u003e\n\u003ch2\u003eWhy Buy From EMIS+\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eNurse-led Singapore medical supply store — clinical expertise you can trust.\u003c\/li\u003e\n\u003cli\u003eAuthentic products with fast island-wide delivery across Singapore.\u003c\/li\u003e\n\u003cli\u003eBulk and recurring orders for home care and nursing facilities are welcome.\u003c\/li\u003e\n\u003cli\u003eQuestions about Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore? Our team is here to help via \u003ca href=\"https:\/\/emis.asia\"\u003eemis.asia\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore used for?\u003c\/strong\u003e\u003cbr\u003eAkkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore is a dietary supplement stocked by EMIS+, Singapore's nurse-led medical supply store. Supplements are intended to support general health and wellbeing and are not a substitute for medical treatment. Always consult your doctor or pharmacist before starting any new supplement, especially if you are pregnant, nursing, or taking medication.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow should I take Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore?\u003c\/strong\u003e\u003cbr\u003eFollow the dosage instructions printed on the Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore packaging, or take as directed by your doctor or pharmacist. Do not exceed the recommended dose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhere can I buy Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore in Singapore?\u003c\/strong\u003e\u003cbr\u003eAkkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore is available from EMIS+ at emis.asia — a nurse-led Singapore medical supply store with fast island-wide delivery. Bulk and recurring orders are welcome. Contact us via emis.asia.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/emis.asia\"\u003e\u003cstrong\u003eShop with EMIS+ at emis.asia →\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore is a dietary supplement stocked by EMIS+, Singapore's nurse-led medical supply store. Supplements are intended to support general health and wellbeing and are not a substitute for medical treatment. Always consult your doctor or pharmacist before starting any new supplement, especially if you are pregnant, nursing, or taking medication.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions printed on the Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore packaging, or take as directed by your doctor or pharmacist. Do not exceed the recommended dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Akkermansia Muciniphila Probiotic Capsules 30s | Gut Health Singapore is available from EMIS+ at emis.asia — a nurse-led Singapore medical supply store with fast island-wide delivery. Bulk and recurring orders are welcome. Contact us via emis.asia.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Pendulum","offers":[{"title":"Default Title","offer_id":41823311822926,"sku":"","price":85.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/sg-11134207-7rbn3-lnniti4ey3744e.jpg?v=1750131703"},{"product_id":"pendulum-akkermansia-500-pro-30-capsules","title":"Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules)","description":"\u003cp data-path-to-node=\"7\"\u003e\u003cb data-path-to-node=\"7\" data-index-in-node=\"12\"\u003eDaily Probiotic for Advanced Gut Function\u003c\/b\u003e Pendulum Akkermansia contains \u003ci data-path-to-node=\"7\" data-index-in-node=\"84\"\u003eAkkermansia muciniphila\u003c\/i\u003e, a specialized strain formulated to support the gut lining and promote a healthy microbiome ecosystem. This maximum-strength formula delivers live cultures in a targeted delivery system.\u003c\/p\u003e\n\u003cp data-path-to-node=\"8\"\u003e\u003cb data-path-to-node=\"8\" data-index-in-node=\"0\"\u003eKey Features:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"9\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,0,0\"\u003e\u003cb data-path-to-node=\"9,0,0\" data-index-in-node=\"0\"\u003eTargeted Strain:\u003c\/b\u003e Contains live \u003ci data-path-to-node=\"9,0,0\" data-index-in-node=\"31\"\u003eAkkermansia muciniphila\u003c\/i\u003e, a beneficial bacterium naturally found in the gut.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,1,0\"\u003e\u003cb data-path-to-node=\"9,1,0\" data-index-in-node=\"0\"\u003eDaily Support:\u003c\/b\u003e Formulated for daily maintenance of microbiome balance.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,0\"\u003e\u003cb data-path-to-node=\"9,2,0\" data-index-in-node=\"0\"\u003eVegetarian Friendly:\u003c\/b\u003e Encapsulated in hypromellose plant-based capsules.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,3,0\"\u003e\u003cb data-path-to-node=\"9,3,0\" data-index-in-node=\"0\"\u003eQuality Assured:\u003c\/b\u003e Sealed for freshness and potency.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"10\"\u003e\u003cb data-path-to-node=\"10\" data-index-in-node=\"0\"\u003eIngredients\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"11\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,0,0\"\u003e\u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"0\"\u003eActive:\u003c\/b\u003e \u003ci data-path-to-node=\"11,0,0\" data-index-in-node=\"8\"\u003eAkkermansia muciniphila\u003c\/i\u003e (Live Strain)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,1,0\"\u003e\u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"0\"\u003eOther Ingredients:\u003c\/b\u003e Microcrystalline cellulose, hypromellose (vegetarian capsule), L-leucine, silica.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eSuggested Use\u003c\/b\u003e Adults: Take 1 capsule daily with food. \u003ci data-path-to-node=\"12\" data-index-in-node=\"54\"\u003eStorage:\u003c\/i\u003e Keep refrigerated to maintain culture viability and quality.\u003c\/p\u003e\n\u003cp data-path-to-node=\"13\"\u003e\u003cb data-path-to-node=\"13\" data-index-in-node=\"0\"\u003eSafety Information\u003c\/b\u003e Consult a healthcare professional before use if you are pregnant, nursing, or taking medication. Do not use if the safety seal is damaged or missing. Keep out of reach of children.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What are the benefits of Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules) for digestive health?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules) by Pendulum promotes gut microbiome diversity, supports digestive comfort, and strengthens the gut-immune axis. For individuals with digestive concerns such as IBS, bloating, or irregular bowel habits, targeted gut health supplementation may complement a balanced diet and lifestyle. Always consult a doctor or dietitian before starting supplements for digestive conditions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Who should take Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules)?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules) may benefit adults seeking to support digestive health, those recovering from antibiotic use, individuals with irregular bowel habits, or those with conditions affecting gut microbiome balance. It is not a substitute for medical treatment. Consult your GP or gastroenterologist — available at SGH, NUH, Mount Elizabeth, and Raffles Hospital in Singapore — for personalised advice.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules) for best results?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions on the Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules) packaging or as directed by your healthcare provider. Consistency is key — most gut health supplements take 4–8 weeks of regular use to show measurable benefits. Store as directed on the label. Do not exceed the recommended daily dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules) in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Pendulum Akkermansia Muciniphila Probiotic - Advanced Gut Support Supplement (30 Capsules) is available at EMIS+ (emis.asia) with fast Singapore island-wide delivery. We carry a curated range of clinically-informed digestive health supplements. Visit emis.asia or contact our team for product recommendations.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Pendulum","offers":[{"title":"100 Pro","offer_id":43220949237838,"sku":null,"price":85.0,"currency_code":"SGD","in_stock":false},{"title":"500 Pro","offer_id":43220949270606,"sku":null,"price":100.09,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/49_d90555e6-7277-4805-980c-49237d509e59.png?v=1780451884"},{"product_id":"pendulum-metabolic-daily-pro-30-capsules-metabolism-gut-health-probiotic-emis","title":"Pendulum Metabolic Daily Pro (30 Capsules) | Metabolism \u0026 Gut Health Probiotic | EMIS+","description":"\u003cdiv style=\"background:#f0f7ff;border-left:4px solid #0057a8;padding:16px 20px;margin:0 0 20px;border-radius:4px;\"\u003e\n\u003cstrong\u003eQuick answer:\u003c\/strong\u003e Pendulum Metabolic Daily Pro (30 Capsules) is available in Singapore from EMIS+ (\u003ca href=\"https:\/\/emis.asia\"\u003eemis.asia\u003c\/a\u003e), a nurse-led medical and wellness supplier offering genuine stock and fast local delivery. See the details and FAQs below, and consult a healthcare professional for advice specific to your needs.\u003c\/div\u003e\n\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e Pendulum Metabolic Daily Pro is a five-strain medical probiotic capsule designed by Pendulum Therapeutics for the dietary management of metabolic and gut health. It contains live Akkermansia muciniphila WB-STR-0001 alongside Clostridium butyricum, Clostridium beijerinckii, Anaerobutyricum hallii (formerly Eubacterium hallii) and Bifidobacterium infantis — a butyrate- and mucin-producing consortium implicated in glucose regulation, gut-barrier integrity and short-chain fatty acid (SCFA) signalling. The same five-strain platform underpins Pendulum's published 12-week, multi-site, double-blind, placebo-controlled randomised trial in adults with type 2 diabetes, which reported a 0.6 percentage-point reduction in HbA1c and a 33% reduction in post-prandial glucose excursions versus placebo.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eMetabolic Daily Pro is the practitioner channel formulation of Pendulum Therapeutics' multi-strain probiotic platform, targeted at adults seeking adjunctive nutritional support for metabolic health. The formulation is a proprietary \"next-generation\" probiotic, distinguished from conventional Lactobacillus\/Bifidobacterium products by the inclusion of strict-anaerobe colonic species — most notably Akkermansia muciniphila — that have historically been difficult to manufacture and stabilise in oral dosage form.\u003c\/p\u003e\n\u003cp\u003eThe five strains were selected for their complementary mechanisms in the gut: Akkermansia muciniphila supports mucin layer turnover and intestinal-barrier integrity; Clostridium butyricum and Anaerobutyricum hallii produce butyrate, the principal SCFA energy substrate of colonocytes; Clostridium beijerinckii contributes to acetate\/butyrate production; and Bifidobacterium infantis supports infant-type bifidobacterial cross-feeding. Capsules are delivered in an acid-resistant shell to protect viability through gastric transit. The product is intended to be used as part of a balanced diet and is not a substitute for prescribed glucose-lowering therapy.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%;\" cellspacing=\"0\" cellpadding=\"6\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eManufacturer\u003c\/th\u003e\n\u003ctd\u003ePendulum Therapeutics, Inc. (United States)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eProduct\u003c\/th\u003e\n\u003ctd\u003eMetabolic Daily Pro — multi-strain probiotic capsule (practitioner channel)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003ePack size\u003c\/th\u003e\n\u003ctd\u003e30 capsules per bottle (one-month supply at 1 capsule\/day)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eActive strains\u003c\/th\u003e\n\u003ctd\u003eAkkermansia muciniphila WB-STR-0001; Clostridium butyricum; Clostridium beijerinckii; Anaerobutyricum hallii; Bifidobacterium infantis\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eMechanism class\u003c\/th\u003e\n\u003ctd\u003eMucin-degrading and butyrate-producing consortium; SCFA and gut-barrier supportive\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eDosage form\u003c\/th\u003e\n\u003ctd\u003eAcid-resistant capsule (gastric-protective shell)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eDietary attributes\u003c\/th\u003e\n\u003ctd\u003eVegan capsule shell; gluten-free; non-GMO; soy-free; dairy-free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eStorage\u003c\/th\u003e\n\u003ctd\u003eRefrigerate at 2–8°C to preserve viable cell count; protect from heat and humidity\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eManufacturing standards\u003c\/th\u003e\n\u003ctd\u003eManufactured under cGMP (US FDA 21 CFR Part 111 dietary supplement regulations); supplier facilities operate to NSF\/IFS food-safety standards\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eRegulatory positioning\u003c\/th\u003e\n\u003ctd\u003eMarketed as a medical probiotic dietary supplement in the United States. In Singapore, classified by HSA as a health supplement under the Health Products Act and not as a registered therapeutic product or medical device. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eKey clinical evidence\u003c\/th\u003e\n\u003ctd\u003ePerraudeau et al., BMJ Open Diabetes Research \u0026amp; Care 2020 — 12-week, randomised, double-blind, placebo-controlled trial; HbA1c −0.6 percentage points and post-prandial glucose AUC −33% versus placebo in adults with type 2 diabetes.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eKey Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAdjunctive nutritional support of glycaemic and post-prandial glucose response in adults with diet-controlled or metformin-managed type 2 diabetes (under clinician supervision).\u003c\/li\u003e\n\u003cli\u003eMicrobiome support in adults with metabolic syndrome features — central adiposity, dyslipidaemia, prediabetes — as part of a structured lifestyle programme.\u003c\/li\u003e\n\u003cli\u003eRestoration of mucin-degrading and butyrate-producing bacterial niches following broad-spectrum antibiotic exposure.\u003c\/li\u003e\n\u003cli\u003eAdjunctive support after weight-loss interventions (caloric restriction, GLP-1 receptor agonist therapy, bariatric surgery) where intestinal barrier and SCFA function are clinically relevant.\u003c\/li\u003e\n\u003cli\u003ePractitioner-led functional and integrative medicine programmes addressing gut-barrier dysfunction.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat clinical evidence supports the formulation?\u003c\/strong\u003e\u003cbr\u003eThe five-strain Pendulum platform was evaluated in a 12-week, multi-site, double-blind, randomised, placebo-controlled clinical trial in adults with type 2 diabetes (Perraudeau et al., 2020, BMJ Open Diabetes Research \u0026amp; Care). The active arm achieved a statistically significant reduction in HbA1c of approximately 0.6 percentage points and a 33% reduction in post-prandial glucose AUC versus placebo on background standard care.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does this differ from conventional probiotics?\u003c\/strong\u003e\u003cbr\u003eStandard probiotics are dominated by Lactobacillus and Bifidobacterium strains, which colonise the small intestine. Metabolic Daily Pro contains strict colonic anaerobes — including Akkermansia muciniphila — whose mucin-degradation and butyrate-production pathways are mechanistically tied to gut-barrier integrity and metabolic homeostasis rather than simple lactic-acid fermentation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy does the product require refrigeration?\u003c\/strong\u003e\u003cbr\u003eStrict anaerobes such as Akkermansia muciniphila are sensitive to oxygen, heat and humidity. Refrigeration at 2–8°C and acid-resistant encapsulation preserve viable colony-forming units (CFU) over the labelled shelf life. Storage at room temperature for short periods during transit is acceptable per the manufacturer's stability data.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs it safe with metformin or other glucose-lowering therapy?\u003c\/strong\u003e\u003cbr\u003eThe Pendulum trial enrolled patients on stable metformin and standard care. As with any dietary supplement that may influence glycaemic response, patients on insulin, sulphonylureas or GLP-1 receptor agonists should be reviewed by their treating clinician for hypoglycaemia risk and dose-titration considerations. The product is not a substitute for prescribed therapy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is the regulatory status in Singapore?\u003c\/strong\u003e\u003cbr\u003eIn Singapore the product is supplied as a health supplement under the Health Products Act and is not registered as a therapeutic product or medical device with the Health Sciences Authority (HSA). The manufacturer operates under US FDA 21 CFR Part 111 cGMP requirements for dietary supplements. Essential Medical International Supplies Pte Ltd (emis.asia) is the authorised reseller and recommends use under qualified healthcare-professional guidance.\u003c\/p\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What clinical evidence supports the formulation?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"The five-strain Pendulum platform was evaluated in a 12-week, multi-site, double-blind, randomised, placebo-controlled clinical trial in adults with type 2 diabetes (Perraudeau et al., 2020, BMJ Open Diabetes Research \u0026 Care). The active arm achieved a statistically significant reduction in HbA1c of approximately 0.6 percentage points and a 33% reduction in post-prandial glucose AUC versus placebo on background standard care.\"}}, {\"@type\": \"Question\", \"name\": \"How does this differ from conventional probiotics?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Standard probiotics are dominated by Lactobacillus and Bifidobacterium strains, which colonise the small intestine. Metabolic Daily Pro contains strict colonic anaerobes — including Akkermansia muciniphila — whose mucin-degradation and butyrate-production pathways are mechanistically tied to gut-barrier integrity and metabolic homeostasis rather than simple lactic-acid fermentation.\"}}, {\"@type\": \"Question\", \"name\": \"Why does the product require refrigeration?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Strict anaerobes such as Akkermansia muciniphila are sensitive to oxygen, heat and humidity. Refrigeration at 2–8°C and acid-resistant encapsulation preserve viable colony-forming units (CFU) over the labelled shelf life. Storage at room temperature for short periods during transit is acceptable per the manufacturer's stability data.\"}}, {\"@type\": \"Question\", \"name\": \"Is it safe with metformin or other glucose-lowering therapy?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"The Pendulum trial enrolled patients on stable metformin and standard care. As with any dietary supplement that may influence glycaemic response, patients on insulin, sulphonylureas or GLP-1 receptor agonists should be reviewed by their treating clinician for hypoglycaemia risk and dose-titration considerations. The product is not a substitute for prescribed therapy.\"}}, {\"@type\": \"Question\", \"name\": \"What is the regulatory status in Singapore?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"In Singapore the product is supplied as a health supplement under the Health Products Act and is not registered as a therapeutic product or medical device with the Health Sciences Authority (HSA). The manufacturer operates under US FDA 21 CFR Part 111 cGMP requirements for dietary supplements. Essential Medical International Supplies Pte Ltd (emis.asia) is the authorised reseller and recommends use under qualified healthcare-professional guidance.\"}}]}\n\u003c\/script\u003e","brand":"Pendulum","offers":[{"title":"Default Title","offer_id":43510078144590,"sku":null,"price":115.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/emisproductlisting_74.jpg?v=1773109318"}],"url":"https:\/\/th.emis.asia\/en\/collections\/pendulum.oembed","provider":"EMIS+","version":"1.0","type":"link"}