{"title":"Customized Probiotic","description":"\u003cdiv class=\"col-aeo\"\u003e\n\u003cp\u003e\u003cstrong\u003eCustomised probiotic options let you match strains and strengths to specific gut-health needs.\u003c\/strong\u003e EMIS+ supplies probiotics in Singapore, including well-researched strains for adults and children.\u003c\/p\u003e\n\u003ch2\u003eFinding the right probiotic\u003c\/h2\u003e\n\u003cp\u003eThe most effective probiotic is the strain matched to your need, taken consistently. Explore our full \u003ca href=\"\/en\/collections\/beneficial-probiotics\"\u003eprobiotics range\u003c\/a\u003e (Bioflor, LactoGG, Vivomixx) and \u003ca href=\"\/en\/collections\/kids-probiotics\"\u003ekids probiotics\u003c\/a\u003e, and ask your doctor or pharmacist for guidance if you have a medical condition.\u003c\/p\u003e\n\u003c\/div\u003e","products":[{"product_id":"amili-enhanced-gut-microbiome-test","title":"AMILI Enhanced Gut Microbiome Test","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e The AMILI Enhanced Gut Microbiome Test is a Singapore-developed, at-home stool collection diagnostic that profiles intestinal bacterial composition using validated 16S rRNA gene sequencing. Results are interpreted against the largest multi-ethnic Asian gut microbiome reference database (GUTOMICS™), providing population-relevant insights across digestion, immunity, metabolism, and gut-brain axis function. The test produces a clinician-grade report with personalised dietary, lifestyle, and probiotic recommendations within 4-5 weeks of sample receipt.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eThe AMILI Enhanced Gut Microbiome Test is a precision-medicine diagnostic developed by AMILI Pte Ltd, a Singapore-headquartered microbiome biotechnology company spun out from the Singapore Stool Bank. It applies next-generation 16S rRNA gene amplicon sequencing to a single self-collected stool specimen to enumerate the relative abundance of bacterial taxa colonising the lower gastrointestinal tract. Unlike Western-derived microbiome panels, AMILI benchmarks each sample against GUTOMICS™, a proprietary database of more than 10,000 multi-ethnic Asian gut microbiomes curated in collaboration with A*STAR and regional clinical partners.\u003c\/p\u003e\n\u003cp\u003eThe Enhanced report quantifies four core functional axes derived from peer-reviewed metagenomic literature: Digestive Health (short-chain fatty acid producers, fibre fermenters), Immunity \u0026amp; Inflammation (regulatory taxa, opportunistic pathogen markers), Metabolic Health (bile acid metabolism, glucose homeostasis indicators), and Brain Health (gut-brain axis modulators including serotonin precursors). Each parameter is contextualised against age-, sex-, and ethnicity-matched cohorts. The clinician version of the report provides actionable dietary fibre prescriptions, prebiotic targets, and a personalised AMILI probiotic strain recommendation calibrated to the patient's deficiency profile.\u003c\/p\u003e\n\u003ch2\u003eTechnical Specifications\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%;\" cellspacing=\"0\" cellpadding=\"6\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eManufacturer\u003c\/th\u003e\n\u003ctd\u003eAMILI Pte Ltd, Singapore\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eTest Type\u003c\/th\u003e\n\u003ctd\u003eAt-home stool collection, laboratory-processed gut microbiome profiling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eSequencing Platform\u003c\/th\u003e\n\u003ctd\u003e16S rRNA gene amplicon sequencing (V3-V4 region) on Illumina platform\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eReference Database\u003c\/th\u003e\n\u003ctd\u003eGUTOMICS™ multi-ethnic Asian gut microbiome reference (\u0026gt;10,000 samples)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eFunctional Axes Reported\u003c\/th\u003e\n\u003ctd\u003eDigestion, Immunity \u0026amp; Metabolism, Brain Health, Probiotic Match\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eSample Type\u003c\/th\u003e\n\u003ctd\u003eSingle stool specimen, stabilised in proprietary preservative buffer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eCollection Method\u003c\/th\u003e\n\u003ctd\u003eSelf-collection at home using supplied kit; courier or drop-off return\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eSample Stability\u003c\/th\u003e\n\u003ctd\u003eUp to 14 days at ambient temperature once stabilised\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eTurnaround Time\u003c\/th\u003e\n\u003ctd\u003e4-5 weeks from laboratory receipt to digital report\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eEligible Age\u003c\/th\u003e\n\u003ctd\u003e5 years and above (gut microbiome maturation threshold)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eQuality System\u003c\/th\u003e\n\u003ctd\u003eISO 15189-aligned laboratory workflow; ISO 13485 quality management\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eRegulatory\u003c\/th\u003e\n\u003ctd\u003eHSA Singapore notified; CLIA-equivalent laboratory standards; data handling per Singapore PDPA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eReport Format\u003c\/th\u003e\n\u003ctd\u003eDigital PDF (patient and clinician versions) with personalised recommendations\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBaseline gut microbiome characterisation for patients with chronic digestive complaints (IBS, functional dyspepsia, chronic constipation, intermittent diarrhoea)\u003c\/li\u003e\n\u003cli\u003eWorkup for suspected gut-immunity dysregulation (recurrent infections, atopic dermatitis, allergic rhinitis, food intolerance)\u003c\/li\u003e\n\u003cli\u003eMetabolic health profiling in pre-diabetes, dyslipidaemia, or metabolic syndrome management\u003c\/li\u003e\n\u003cli\u003ePre- and post-intervention monitoring for dietary modification, antibiotic recovery, or targeted probiotic therapy\u003c\/li\u003e\n\u003cli\u003eAdjunct assessment in mood, sleep, and cognition concerns where the gut-brain axis is clinically relevant\u003c\/li\u003e\n\u003cli\u003eRoutine wellness screening as part of an integrated functional medicine or longevity programme\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhy is an Asian reference database important for interpreting my results?\u003c\/h3\u003e\n\u003cp\u003eGut microbiome composition is strongly shaped by diet, ethnicity, and geography. Reference ranges built from European or North American cohorts systematically misclassify Asian samples because key fibre-fermenting taxa (e.g. Prevotella copri, Faecalibacterium prausnitzii) are present at different baseline abundances. AMILI's GUTOMICS™ database, validated in peer-reviewed studies with A*STAR, allows population-appropriate interpretation that is clinically defensible for Singaporean and broader Southeast Asian patients.\u003c\/p\u003e\n\u003ch3\u003eIs 16S rRNA sequencing clinically reliable?\u003c\/h3\u003e\n\u003cp\u003e16S rRNA gene sequencing is the established methodology for genus- and family-level bacterial profiling, recommended by the Human Microbiome Project and used in over 30,000 published studies. It does not resolve to strain level (which requires whole-genome shotgun sequencing) but is appropriate, cost-effective, and reproducible for the functional reporting AMILI delivers. Laboratory workflows are aligned with ISO 15189 medical laboratory standards.\u003c\/p\u003e\n\u003ch3\u003eHow does this differ from a stool culture or faecal calprotectin test?\u003c\/h3\u003e\n\u003cp\u003eStool culture detects only a narrow range of culturable pathogens; faecal calprotectin quantifies neutrophil-derived inflammation. The AMILI Enhanced test profiles the entire bacterial community at relative-abundance level, enabling assessment of dysbiosis patterns, diversity indices (Shannon, Simpson), and functional capacity that conventional microbiology cannot reveal. It complements rather than replaces these established assays.\u003c\/p\u003e\n\u003ch3\u003eIs the test reimbursable under Singapore Medisave or private insurance?\u003c\/h3\u003e\n\u003cp\u003eThe AMILI Enhanced Gut Microbiome Test is a wellness diagnostic and is generally not Medisave-claimable. Some private integrated shield plans and corporate wellness programmes (including the Manulife-AMILI partnership) provide partial reimbursement; patients should confirm coverage with their insurer and obtain a referral letter from a registered Singapore medical practitioner where required.\u003c\/p\u003e\n\u003ch3\u003eHow should the report be acted upon clinically?\u003c\/h3\u003e\n\u003cp\u003eReports are designed for review with a qualified healthcare provider, registered dietitian, or naturopath. AMILI provides clinician onboarding materials and a Singapore-based scientific advisory team. Recommendations should be integrated with full clinical history, dietary assessment, and existing pharmacotherapy; the test is not a substitute for diagnostic endoscopy, imaging, or pathogen-specific assays where indicated.\u003c\/p\u003e\n\n\u003chr\u003e\n\u003ch2\u003eWhy Buy From EMIS+\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eNurse-led Singapore medical supply store — clinical expertise you can trust.\u003c\/li\u003e\n\u003cli\u003eAuthentic products with fast island-wide delivery across Singapore.\u003c\/li\u003e\n\u003cli\u003eBulk and recurring orders for home care and nursing facilities are welcome.\u003c\/li\u003e\n\u003cli\u003eQuestions about AMILI Enhanced Gut Microbiome Test? Our team is here to help via \u003ca href=\"https:\/\/emis.asia\"\u003eemis.asia\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is AMILI Enhanced Gut Microbiome Test used for?\u003c\/strong\u003e\u003cbr\u003eAMILI Enhanced Gut Microbiome Test is a dietary supplement stocked by EMIS+, Singapore's nurse-led medical supply store. Supplements are intended to support general health and wellbeing and are not a substitute for medical treatment. Always consult your doctor or pharmacist before starting any new supplement, especially if you are pregnant, nursing, or taking medication.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow should I take AMILI Enhanced Gut Microbiome Test?\u003c\/strong\u003e\u003cbr\u003eFollow the dosage instructions printed on the AMILI Enhanced Gut Microbiome Test packaging, or take as directed by your doctor or pharmacist. Do not exceed the recommended dose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhere can I buy AMILI Enhanced Gut Microbiome Test in Singapore?\u003c\/strong\u003e\u003cbr\u003eAMILI Enhanced Gut Microbiome Test is available from EMIS+ at emis.asia — a nurse-led Singapore medical supply store with fast island-wide delivery. Bulk and recurring orders are welcome. Contact us via emis.asia.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/emis.asia\"\u003e\u003cstrong\u003eShop with EMIS+ at emis.asia →\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is AMILI Enhanced Gut Microbiome Test used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"AMILI Enhanced Gut Microbiome Test is a dietary supplement stocked by EMIS+, Singapore's nurse-led medical supply store. Supplements are intended to support general health and wellbeing and are not a substitute for medical treatment. Always consult your doctor or pharmacist before starting any new supplement, especially if you are pregnant, nursing, or taking medication.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take AMILI Enhanced Gut Microbiome Test?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions printed on the AMILI Enhanced Gut Microbiome Test packaging, or take as directed by your doctor or pharmacist. Do not exceed the recommended dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy AMILI Enhanced Gut Microbiome Test in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"AMILI Enhanced Gut Microbiome Test is available from EMIS+ at emis.asia — a nurse-led Singapore medical supply store with fast island-wide delivery. Bulk and recurring orders are welcome. Contact us via emis.asia.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Amili","offers":[{"title":"Default Title","offer_id":43232608321614,"sku":null,"price":350.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/AMILI_Enhanced_Gut_Microbiome_Test_13356eae-7a55-4a77-a3e2-dc8a16aed9de.png?v=1767038461"},{"product_id":"amili-probiotics-formulation-1","title":"AMILI Probiotics Formulation 1 for Immune and Gut Health Support","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e AMILI Probiotics Formulation 1 is a multi-strain synbiotic supplement containing 9 billion CFU of clinically studied probiotic bacteria, formulated specifically for Asian gut microbiome profiles based on data from Asia's largest multi-ethnic microbiome study. The formulation delivers Bifidobacterium animalis subsp. lactis, Lactiplantibacillus plantarum, Bifidobacterium longum subsp. longum, and Streptococcus salivarius subsp. thermophilus in delayed-release capsules to support immune defence and gut barrier integrity. Indicated for daily immune and digestive health maintenance in adults seeking evidence-based microbiome support.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eAMILI Probiotics Formulation 1 is a precision-formulated synbiotic supplement developed by AMILI Pte Ltd, a Singapore-based microbiome science company. Unlike generic probiotic supplements derived from Western population datasets, this formulation was developed using insights from Asia's largest multi-ethnic gut microbiome reference database, encompassing diverse dietary patterns, genetic backgrounds, and environmental exposures across Southeast Asian populations. This population-specific approach ensures that the selected bacterial strains are relevant to the gut ecology of individuals living in tropical Asian environments.\u003c\/p\u003e\n\u003cp\u003eThe formulation combines four probiotic strains with prebiotic fructo-oligosaccharide (FOS) and citrus aurantium extract in a delayed-release capsule delivery system. The delayed-release mechanism protects viable organisms through gastric acid transit, ensuring colonisation potential in the lower gastrointestinal tract where immunomodulatory interactions with gut-associated lymphoid tissue (GALT) are most significant. Bifidobacterium animalis subsp. lactis, the lead strain in this formulation, has demonstrated efficacy in randomised controlled trials for reducing upper respiratory tract infection incidence and enhancing natural killer cell activity.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold; width: 35%;\"\u003eManufacturer\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eAMILI Pte Ltd, Singapore\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProduct Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eMulti-Strain Synbiotic Supplement (Probiotic + Prebiotic)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eTotal CFU Count\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e9 Billion CFU per capsule (at time of manufacture)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProbiotic Strains\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eBifidobacterium animalis subsp. lactis, Lactiplantibacillus plantarum, Bifidobacterium longum subsp. longum, Streptococcus salivarius subsp. thermophilus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePrebiotic Component\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFructo-oligosaccharide (FOS) Powder 95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAdditional Ingredients\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eCitrus Aurantium Extract (Orange Peel), Guar Gum\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsule Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDelayed-Release Vegetarian Capsule (acid-resistant)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eServing Size\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e1 capsule daily\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsules Per Pack\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e30 capsules (30-day supply)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eStore in a cool, dry place below 25°C. Refrigeration recommended after opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAllergen Information\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFree from gluten, dairy, soy, nuts, and artificial preservatives\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eRegulatory Compliance\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eManufactured under ISO 22000 food safety management standards; GMP-certified production facility; compliant with Singapore Food Agency (SFA) regulations for health supplements; HSA Singapore notification for health supplements\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eResearch Foundation\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDeveloped from Asia's largest multi-ethnic microbiome reference database (AMILI BioCloud)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePackaging\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eSealed bottle with desiccant, tamper-evident closure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications and Key Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDaily immune system maintenance for adults in tropical climates, where gut microbiome composition is influenced by heat, humidity, and regional dietary patterns\u003c\/li\u003e\n\u003cli\u003eReduction of upper respiratory tract infection frequency and duration through enhanced mucosal immune surveillance mediated by B. animalis subsp. lactis\u003c\/li\u003e\n\u003cli\u003ePost-antibiotic gut microbiome restoration to re-establish commensal bacterial populations disrupted by broad-spectrum antimicrobial therapy\u003c\/li\u003e\n\u003cli\u003eSupport for individuals with suboptimal gut diversity scores identified through AMILI Enhanced Gut Microbiome Test or equivalent metagenomic profiling\u003c\/li\u003e\n\u003cli\u003eAdjunctive digestive health support for functional gastrointestinal symptoms including irregular bowel habits and mild abdominal discomfort\u003c\/li\u003e\n\u003cli\u003eGut barrier integrity maintenance in adults experiencing dietary transitions, travel-related microbiome disruption, or elevated psychosocial stress\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eHow does AMILI Formulation 1 differ from generic over-the-counter probiotics?\u003c\/h3\u003e\n\u003cp\u003eAMILI Formulation 1 was developed using strain selection informed by Asia's largest multi-ethnic gut microbiome database, rather than relying on Western population references that may not reflect the microbial ecology of individuals in Southeast Asia. The delayed-release capsule technology ensures bacterial viability through gastric acid transit, addressing a common limitation of standard probiotic capsules where a significant proportion of organisms are inactivated before reaching the colon. Each strain included has been selected based on published clinical evidence for immunomodulatory activity, and the prebiotic FOS component provides substrate to support colonisation of the delivered organisms.\u003c\/p\u003e\n\u003ch3\u003eCan AMILI Formulation 1 be taken alongside the AMILI Enhanced Gut Microbiome Test?\u003c\/h3\u003e\n\u003cp\u003eYes. AMILI recommends completing the Enhanced Gut Microbiome Test prior to initiating probiotic supplementation to establish a baseline microbial profile. The test report may specifically recommend Formulation 1 based on individual gut diversity scores and immune-related biomarkers. Follow-up testing after 3-6 months of supplementation can quantify changes in microbial composition. Formulation 1 is the most commonly recommended formulation for individuals with general immune and digestive health optimisation goals. For personalised recommendations, consult with a healthcare professional familiar with microbiome-guided supplementation protocols.\u003c\/p\u003e\n\u003ch3\u003eWhat is the recommended duration for supplementation?\u003c\/h3\u003e\n\u003cp\u003eConsistent daily supplementation for a minimum of 8-12 weeks is recommended to observe measurable changes in gut microbial composition and immune parameters. The World Gastroenterology Organisation (WGO) Global Guidelines on Probiotics and Prebiotics note that probiotic effects are strain-specific and duration-dependent, with most clinical trial protocols employing supplementation periods of 8 weeks or longer. Continued supplementation beyond the initial period may be appropriate for sustained immune support, particularly during seasonal infection peaks or periods of elevated stress.\u003c\/p\u003e\n\u003ch3\u003eIs this product suitable for individuals with food allergies or dietary restrictions?\u003c\/h3\u003e\n\u003cp\u003eAMILI Formulation 1 is formulated free from common allergens including gluten, dairy, soy, and nuts. The capsule shell is vegetarian-compatible. The product contains no artificial colours, flavours, or preservatives. Individuals with citrus sensitivity should note the inclusion of Citrus Aurantium Extract (orange peel extract) as a prebiotic component. As with any health supplement, individuals with underlying medical conditions, those on immunosuppressive therapy, or pregnant and breastfeeding women should consult their healthcare provider before commencing supplementation.\u003c\/p\u003e\n\u003ch3\u003eWhere can healthcare professionals and clinics in Singapore procure AMILI Probiotics?\u003c\/h3\u003e\n\u003cp\u003eAMILI Probiotics Formulation 1 is available through EMIS (Essential Medical International Supplies Pte Ltd), an authorised distributor in Singapore. Healthcare professionals, clinics, and wellness centres can arrange institutional procurement with volume pricing. The product is classified as a health supplement under the Singapore Health Sciences Authority (HSA) regulatory framework. EMIS provides documentation including Certificates of Analysis and batch traceability records for institutional purchasers requiring quality assurance documentation.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is AMILI Probiotics Formulation 1 for Immune and Gut Health Support?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"AMILI Probiotics Formulation 1 for Immune and Gut Health Support is a dietary supplement available from EMIS+ (emis.asia) in Singapore. Supplements are intended to complement a balanced diet and are not meant to diagnose, treat, cure or prevent any disease. Always read the label and use only as directed.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take AMILI Probiotics Formulation 1 for Immune and Gut Health Support?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage on the product label, or take as advised by your doctor, pharmacist or a qualified healthcare professional, and do not exceed the recommended dose. If you are pregnant, breastfeeding, taking medication or managing a health condition, check with your doctor or pharmacist before use.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is AMILI Probiotics Formulation 1 for Immune and Gut Health Support available without prescription in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes. AMILI Probiotics Formulation 1 for Immune and Gut Health Support is available from EMIS+ (emis.asia) without a prescription as a general health supplement. If you take regular medication or have a medical condition, speak with your doctor or pharmacist before starting any new supplement.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy AMILI Probiotics Formulation 1 for Immune and Gut Health Support in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"AMILI Probiotics Formulation 1 for Immune and Gut Health Support is available from EMIS+ at emis.asia, Singapore's nurse-led medical and wellness supply store, with fast island-wide delivery. Bulk orders for clinics and care facilities are welcome — contact us at emis.asia\/pages\/contact.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Amili","offers":[{"title":"Default Title","offer_id":43232608616526,"sku":null,"price":90.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/AMILI_Probiotics_Formulation_1.png?v=1767712263"},{"product_id":"amili-probiotics-formulation-2","title":"Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e AMILI Probiotics Formulation 2 (Complete Health) is a high-potency multi-strain synbiotic containing 12 billion CFU across 6 clinically studied probiotic strains, engineered for comprehensive immune, metabolic, and gut-brain axis support. Developed from Asia's largest multi-ethnic microbiome reference database, this formulation delivers Bifidobacterium longum, B. animalis subsp. lactis, B. breve, Lactiplantibacillus plantarum, Lacticaseibacillus rhamnosus, and Streptococcus thermophilus with prebiotic FOS in delayed-release capsules. Indicated for adults seeking whole-body wellness optimisation through evidence-based microbiome modulation.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eAMILI Probiotics Formulation 2, designated the Complete Health formulation, represents the broadest-spectrum product in the AMILI precision probiotics range. While Formulation 1 targets immune defence specifically, Formulation 2 addresses the interconnected triad of immune regulation, metabolic efficiency, and the gut-brain axis through a six-strain probiotic consortium delivering 12 billion colony-forming units per capsule. This expanded strain diversity reflects current microbiome science indicating that multi-strain formulations produce synergistic metabolic outputs including short-chain fatty acids (SCFAs), neurotransmitter precursors, and immunomodulatory metabolites that single-strain products cannot replicate.\u003c\/p\u003e\n\u003cp\u003eThe formulation was developed by AMILI Pte Ltd using proprietary data from Asia's largest multi-ethnic gut microbiome reference database (AMILI BioCloud), ensuring strain selection is calibrated to the microbial ecology of individuals living in Southeast Asian environments. The inclusion of Bifidobacterium breve and Lacticaseibacillus rhamnosus alongside the core immune strains extends the formulation's functional reach to metabolic parameter modulation and gut-brain signalling via vagal nerve pathways. Delayed-release vegetarian capsules protect organism viability through gastric acid transit, maximising colonic delivery where host-microbe immunological interactions are concentrated.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold; width: 35%;\"\u003eManufacturer\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eAMILI Pte Ltd, Singapore\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProduct Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eMulti-Strain Synbiotic Supplement (Probiotic + Prebiotic)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eTotal CFU Count\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e12 Billion CFU per capsule (at time of manufacture)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProbiotic Strains (6 strains)\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eBifidobacterium longum subsp. longum, Bifidobacterium animalis subsp. lactis, Bifidobacterium breve, Lactiplantibacillus plantarum, Lacticaseibacillus rhamnosus, Streptococcus salivarius subsp. thermophilus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePrebiotic Component\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFructo-oligosaccharide (FOS) Powder 95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAdditional Ingredients\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eCitrus Aurantium Extract (Orange Peel), Guar Gum\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsule Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDelayed-Release Vegetarian Capsule (acid-resistant)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eServing Size\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e1 capsule daily\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsules Per Pack\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e30 capsules (30-day supply)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eStore below 25°C in a cool, dry place. Refrigeration recommended after opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAllergen Information\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFree from gluten, dairy, soy, nuts, and artificial preservatives\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eRegulatory Compliance\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eManufactured under ISO 22000 food safety management standards; GMP-certified production facility; compliant with Singapore Food Agency (SFA) regulations; HSA Singapore health supplement notification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eResearch Foundation\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDeveloped from Asia's largest multi-ethnic microbiome reference database (AMILI BioCloud)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePackaging\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eSealed bottle with desiccant, tamper-evident closure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications and Key Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eComprehensive daily wellness support for adults seeking simultaneous immune, metabolic, and cognitive health optimisation through a single formulation\u003c\/li\u003e\n\u003cli\u003eGut-brain axis modulation for individuals experiencing stress-related digestive disturbances, mood fluctuations, or cognitive fatigue linked to gut dysbiosis\u003c\/li\u003e\n\u003cli\u003eMetabolic parameter support including healthy blood glucose regulation and lipid metabolism mediated by SCFA-producing Bifidobacterium and Lactobacillus strains\u003c\/li\u003e\n\u003cli\u003ePost-antibiotic microbiome reconstitution requiring broad-spectrum recolonisation across multiple bacterial genera\u003c\/li\u003e\n\u003cli\u003eRecommended formulation for individuals with AMILI Enhanced Gut Microbiome Test results indicating multi-domain deficiencies across immune, metabolic, and neurological biomarker categories\u003c\/li\u003e\n\u003cli\u003ePreventive gut health maintenance for healthcare professionals, shift workers, and individuals with irregular dietary patterns that compromise microbial diversity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhat distinguishes Formulation 2 from Formulation 1 in the AMILI range?\u003c\/h3\u003e\n\u003cp\u003eFormulation 1 delivers 9 billion CFU across 4 strains focused primarily on immune defence via Bifidobacterium animalis subsp. lactis. Formulation 2 expands to 12 billion CFU across 6 strains, adding Bifidobacterium breve and Lacticaseibacillus rhamnosus to address metabolic regulation and gut-brain signalling in addition to immune support. Formulation 2 is recommended for individuals whose AMILI microbiome test results indicate deficiencies across multiple functional domains, or for those seeking a single broad-spectrum formulation covering immune, metabolic, and cognitive wellness targets.\u003c\/p\u003e\n\u003ch3\u003eHow does the gut-brain axis mechanism work in this formulation?\u003c\/h3\u003e\n\u003cp\u003eThe gut-brain axis refers to bidirectional communication between the enteric nervous system and the central nervous system, mediated through vagal nerve afferents, neuroactive metabolites, and immune signalling molecules. Specific strains in Formulation 2, particularly Bifidobacterium longum and Lacticaseibacillus rhamnosus, produce gamma-aminobutyric acid (GABA) precursors and modulate tryptophan metabolism, which influences serotonin synthesis. Published research in the journal Frontiers in Neuroscience has demonstrated that these bacterial metabolites can influence mood regulation, stress resilience, and cognitive function through enteroendocrine and immune-mediated pathways.\u003c\/p\u003e\n\u003ch3\u003eCan Formulation 2 be taken concurrently with prescription medications?\u003c\/h3\u003e\n\u003cp\u003eProbiotic supplements are generally well-tolerated alongside most medications. However, individuals taking immunosuppressive agents, chemotherapy, or systemic corticosteroids should consult their prescribing physician before initiating probiotic supplementation, as enhanced immune activation may not be appropriate in immunocompromised states. A 2-hour separation between probiotic capsule ingestion and antibiotic dosing is recommended to minimise direct antimicrobial exposure to the probiotic organisms. The World Gastroenterology Organisation (WGO) guidelines recommend healthcare provider consultation for individuals with central venous catheters, short bowel syndrome, or severe acute pancreatitis.\u003c\/p\u003e\n\u003ch3\u003eWhat is the evidence base for multi-strain probiotic formulations versus single-strain products?\u003c\/h3\u003e\n\u003cp\u003eA systematic review published in Nutrients (2021) analysed 42 randomised controlled trials comparing multi-strain and single-strain probiotics, concluding that multi-strain formulations demonstrated broader functional effects across immune, metabolic, and gastrointestinal endpoints. The proposed mechanism is ecological synergy: different strains occupy complementary metabolic niches, produce diverse SCFAs (acetate, propionate, butyrate), and collectively resist pathogen colonisation more effectively than monocultures. AMILI's six-strain consortium was specifically designed to maximise this synergistic potential based on co-occurrence patterns observed in healthy Asian gut microbiome profiles.\u003c\/p\u003e\n\u003ch3\u003eIs this product available for institutional procurement in Singapore?\u003c\/h3\u003e\n\u003cp\u003eYes. EMIS (Essential Medical International Supplies Pte Ltd) is an authorised Singapore distributor for AMILI precision probiotics. Healthcare institutions, wellness clinics, and integrative medicine practices can arrange B2B procurement with volume pricing. AMILI probiotics are classified as health supplements under the Health Sciences Authority (HSA) Singapore regulatory framework. EMIS provides Certificates of Analysis, batch traceability documentation, and cold-chain logistics support for institutional orders requiring temperature-controlled delivery.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What are the benefits of Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support for digestive health?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support by Amili promotes gut microbiome diversity, supports digestive comfort, and strengthens the gut-immune axis. For individuals with digestive concerns such as IBS, bloating, or irregular bowel habits, targeted gut health supplementation may complement a balanced diet and lifestyle. Always consult a doctor or dietitian before starting supplements for digestive conditions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Who should take Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support may benefit adults seeking to support digestive health, those recovering from antibiotic use, individuals with irregular bowel habits, or those with conditions affecting gut microbiome balance. It is not a substitute for medical treatment. Consult your GP or gastroenterologist — available at SGH, NUH, Mount Elizabeth, and Raffles Hospital in Singapore — for personalised advice.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support for best results?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions on the Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support packaging or as directed by your healthcare provider. Consistency is key — most gut health supplements take 4–8 weeks of regular use to show measurable benefits. Store as directed on the label. Do not exceed the recommended daily dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Complete Health Formulation 2 for Immune Metabolic and Gut Brain Support is available at EMIS+ (emis.asia) with fast Singapore island-wide delivery. We carry a curated range of clinically-informed digestive health supplements. Visit emis.asia or contact our team for product recommendations.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Amili","offers":[{"title":"Default Title","offer_id":43232609108046,"sku":null,"price":90.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/Complete_Health_Formulation_2.png?v=1767712185"},{"product_id":"amili-probiotics-formulation-3","title":"Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e AMILI Probiotics Formulation 3 is a targeted psychobiotic synbiotic containing 12 billion CFU across 5 clinically studied strains, formulated to support cognitive function, stress resilience, and emotional balance through gut-brain axis modulation. The formulation features Lacticaseibacillus paracasei and Lactiplantibacillus plantarum as lead psychobiotic strains, combined with Bifidobacterium breve, Lacticaseibacillus rhamnosus, and Streptococcus thermophilus with prebiotic FOS in delayed-release capsules. Indicated for adults experiencing stress-related cognitive fatigue, mood fluctuations, or anxiety symptoms linked to gut dysbiosis.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eAMILI Probiotics Formulation 3, designated the Brain and Cognitive Health formulation, is a precision psychobiotic supplement targeting the gut-brain axis — the bidirectional communication network between the enteric nervous system and the central nervous system. Emerging clinical evidence demonstrates that specific probiotic strains can modulate neurotransmitter synthesis, hypothalamic-pituitary-adrenal (HPA) axis reactivity, and neuroinflammatory pathways through metabolite production in the gastrointestinal tract. Formulation 3 was engineered to deliver these psychobiotic benefits using strains selected from AMILI's proprietary Asian microbiome reference database.\u003c\/p\u003e\n\u003cp\u003eThe lead strain, Lacticaseibacillus paracasei, has demonstrated anxiolytic properties in randomised controlled trials, with proposed mechanisms including GABA production, cortisol modulation, and anti-inflammatory cytokine upregulation. Lactiplantibacillus plantarum contributes additional serotonin precursor metabolism through tryptophan pathway modulation, while Bifidobacterium breve supports overall gut barrier integrity to prevent systemic translocation of pro-inflammatory endotoxins that can impair cognitive function. The delayed-release vegetarian capsule delivery system ensures viable organism transit through gastric acid to the colonic environment where neuroimmunological interactions are concentrated.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold; width: 35%;\"\u003eManufacturer\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eAMILI Pte Ltd, Singapore\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProduct Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003ePsychobiotic Synbiotic Supplement (Probiotic + Prebiotic)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eTotal CFU Count\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e12 Billion CFU per capsule (at time of manufacture)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProbiotic Strains (5 strains)\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eLacticaseibacillus paracasei, Lactiplantibacillus plantarum, Bifidobacterium breve, Lacticaseibacillus rhamnosus, Streptococcus salivarius subsp. thermophilus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePrebiotic Component\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFructo-oligosaccharide (FOS) Powder 95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAdditional Ingredients\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eCitrus Aurantium Extract (Orange Peel), Guar Gum\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsule Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDelayed-Release Vegetarian Capsule (acid-resistant)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eServing Size\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e1 capsule daily\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsules Per Pack\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e30 capsules (30-day supply)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eStore below 25°C in a cool, dry place. Refrigeration recommended after opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAllergen Information\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFree from gluten, dairy, soy, nuts, and artificial preservatives\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eRegulatory Compliance\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eManufactured under ISO 22000 food safety management standards; GMP-certified production facility; compliant with Singapore Food Agency (SFA) regulations; HSA Singapore health supplement notification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eResearch Foundation\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDeveloped from Asia's largest multi-ethnic microbiome reference database (AMILI BioCloud)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePackaging\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eSealed bottle with desiccant, tamper-evident closure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications and Key Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCognitive fatigue and mental clarity support for professionals experiencing sustained work-related stress, decision fatigue, or concentration difficulties\u003c\/li\u003e\n\u003cli\u003eStress resilience enhancement through HPA axis modulation, targeting cortisol regulation in individuals with chronic psychosocial stress exposure\u003c\/li\u003e\n\u003cli\u003eEmotional balance support for individuals experiencing mild to moderate mood fluctuations, irritability, or anxiety symptoms associated with gut dysbiosis\u003c\/li\u003e\n\u003cli\u003eAdjunctive support alongside cognitive behavioural therapy (CBT) or mindfulness-based interventions for stress and anxiety management\u003c\/li\u003e\n\u003cli\u003eSleep quality optimisation through serotonin and melatonin precursor pathway modulation in individuals with stress-related sleep disturbances\u003c\/li\u003e\n\u003cli\u003eRecommended formulation for individuals with AMILI Enhanced Gut Microbiome Test results indicating deficiencies in psychobiotic-associated bacterial genera\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhat is a psychobiotic and how does Formulation 3 function as one?\u003c\/h3\u003e\n\u003cp\u003eThe term psychobiotic, first defined by Dinan et al. (2013) in Biological Psychiatry, refers to live organisms that, when ingested in adequate quantities, produce a health benefit in patients with psychiatric illness or cognitive dysfunction. Formulation 3 qualifies as a psychobiotic through its inclusion of strains with demonstrated neuroactive metabolite production. Lacticaseibacillus paracasei produces GABA, the primary inhibitory neurotransmitter in the central nervous system, while Lactiplantibacillus plantarum modulates tryptophan-kynurenine metabolism to influence serotonin availability. These metabolites reach the brain via vagal nerve afferents, systemic circulation, and immune signalling cascades originating in the gut-associated lymphoid tissue.\u003c\/p\u003e\n\u003ch3\u003eHow long does it take to notice cognitive or mood improvements?\u003c\/h3\u003e\n\u003cp\u003eClinical trials investigating psychobiotic interventions typically report measurable changes in validated psychological assessment scales (DASS-21, STAI, PSS) after 8-12 weeks of consistent daily supplementation. Initial improvements in digestive comfort and sleep quality may be observed within 2-4 weeks as gut microbial composition begins to shift. The International Scientific Association for Probiotics and Prebiotics (ISAPP) notes that probiotic effects are strain-specific and dose-dependent, and that individual responses vary based on baseline microbiome composition, dietary patterns, and concurrent stress levels. AMILI recommends baseline and follow-up gut microbiome testing to objectively monitor compositional changes.\u003c\/p\u003e\n\u003ch3\u003eCan Formulation 3 be combined with other AMILI formulations?\u003c\/h3\u003e\n\u003cp\u003eAMILI's formulation range is designed to allow stacking based on individual microbiome test results and health priorities. Formulation 3 can be taken alongside Formulation 1 (immune support) or Formulation 4 (digestive health) for individuals with multi-domain health goals. When combining formulations, a healthcare provider familiar with microbiome-guided supplementation can advise on sequencing and dosing intervals. The strains across formulations are complementary rather than redundant, and combined supplementation does not exceed typical probiotic intake thresholds established in clinical safety literature.\u003c\/p\u003e\n\u003ch3\u003eIs there clinical evidence supporting probiotics for mental health?\u003c\/h3\u003e\n\u003cp\u003eA systematic review and meta-analysis published in BMJ Nutrition, Prevention and Health (2020) analysed 34 controlled trials and concluded that probiotic supplementation demonstrated statistically significant reductions in depression and anxiety scores compared to placebo, with effect sizes ranging from small to moderate. The evidence is most robust for multi-strain formulations containing Lactobacillus and Bifidobacterium genera administered for 8 weeks or longer. The European Food Safety Authority (EFSA) and HSA Singapore currently classify probiotics as food supplements rather than therapeutic agents, and AMILI Formulation 3 is not intended to diagnose, treat, or cure any psychiatric condition.\u003c\/p\u003e\n\u003ch3\u003eWhere can I purchase AMILI Formulation 3 in Singapore?\u003c\/h3\u003e\n\u003cp\u003eAMILI Probiotics Formulation 3 is available through EMIS (Essential Medical International Supplies Pte Ltd), an authorised Singapore distributor. Individual consumers can purchase directly through the EMIS online store at emis.asia. Healthcare professionals, integrative medicine practitioners, and wellness clinics can arrange institutional procurement with volume pricing through EMIS. The product is classified as a health supplement under the Health Sciences Authority (HSA) Singapore regulatory framework, and EMIS provides full product documentation for institutional purchasers.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What are the benefits of Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance for digestive health?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance by Amili promotes gut microbiome diversity, supports digestive comfort, and strengthens the gut-immune axis. For individuals with digestive concerns such as IBS, bloating, or irregular bowel habits, targeted gut health supplementation may complement a balanced diet and lifestyle. Always consult a doctor or dietitian before starting supplements for digestive conditions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Who should take Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance may benefit adults seeking to support digestive health, those recovering from antibiotic use, individuals with irregular bowel habits, or those with conditions affecting gut microbiome balance. It is not a substitute for medical treatment. Consult your GP or gastroenterologist — available at SGH, NUH, Mount Elizabeth, and Raffles Hospital in Singapore — for personalised advice.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance for best results?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions on the Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance packaging or as directed by your healthcare provider. Consistency is key — most gut health supplements take 4–8 weeks of regular use to show measurable benefits. Store as directed on the label. Do not exceed the recommended daily dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Brain and Cognitive Health Formulation 3 for Mental Clarity and Emotional Balance is available at EMIS+ (emis.asia) with fast Singapore island-wide delivery. We carry a curated range of clinically-informed digestive health supplements. Visit emis.asia or contact our team for product recommendations.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Amili","offers":[{"title":"Default Title","offer_id":43232609402958,"sku":null,"price":90.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/Brain_and_Cognitive_Health_Formulation_3.png?v=1767712096"},{"product_id":"amili-probiotics-formulation-4","title":"Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e AMILI Probiotics Formulation 4 is a high-potency synbiotic containing 15 billion CFU across 5 clinically studied strains, formulated for digestive health optimisation, microbiota rebalancing, and gut resilience. The formulation is powered by Limosilactobacillus reuteri, a strain with documented anti-inflammatory and antimicrobial properties, combined with Lactiplantibacillus plantarum, Bifidobacterium breve, Lacticaseibacillus rhamnosus, and Streptococcus thermophilus with prebiotic FOS in delayed-release capsules. Indicated for adults with functional gastrointestinal symptoms, post-antibiotic dysbiosis, or microbiome test results indicating reduced digestive health biomarkers.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eAMILI Probiotics Formulation 4, designated the Digestive Health formulation, delivers the highest colony-forming unit count in the AMILI precision probiotics range at 15 billion CFU per capsule. This formulation addresses the foundational layer of gut health — microbial diversity, mucosal barrier integrity, and digestive function — through a five-strain consortium anchored by Limosilactobacillus reuteri. L. reuteri is among the most extensively studied probiotic organisms in gastroenterology, with over 170 published clinical trials documenting its effects on gastrointestinal motility, pathogen inhibition via reuterin production, and intestinal epithelial barrier reinforcement.\u003c\/p\u003e\n\u003cp\u003eDeveloped by AMILI Pte Ltd using strain selection informed by Asia's largest multi-ethnic gut microbiome reference database (AMILI BioCloud), Formulation 4 is calibrated for the digestive health challenges prevalent in Southeast Asian populations, including functional dyspepsia, irregular bowel habits, and antibiotic-associated microbiome disruption. The elevated 15 billion CFU dosage reflects clinical trial protocols for digestive health endpoints, where higher organism counts are associated with more consistent therapeutic responses. Delayed-release vegetarian capsules ensure organism viability through gastric acid transit, delivering viable bacteria to the colonic environment where they can establish colonisation and exert localised anti-inflammatory effects.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold; width: 35%;\"\u003eManufacturer\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eAMILI Pte Ltd, Singapore\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProduct Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eHigh-Potency Synbiotic Supplement (Probiotic + Prebiotic)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eTotal CFU Count\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e15 Billion CFU per capsule (at time of manufacture)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eLead Strain\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eLimosilactobacillus reuteri (formerly Lactobacillus reuteri)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eProbiotic Strains (5 strains)\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eLimosilactobacillus reuteri, Lactiplantibacillus plantarum, Bifidobacterium breve, Lacticaseibacillus rhamnosus, Streptococcus salivarius subsp. thermophilus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePrebiotic Component\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFructo-oligosaccharide (FOS) Powder 95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAdditional Ingredients\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eCitrus Aurantium Extract (Orange Peel), Guar Gum\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsule Type\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDelayed-Release Vegetarian Capsule (acid-resistant)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eServing Size\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e1 capsule daily\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eCapsules Per Pack\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003e30 capsules (30-day supply)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eStore below 25°C in a cool, dry place. Refrigeration recommended after opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eAllergen Information\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eFree from gluten, dairy, soy, nuts, and artificial preservatives\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eRegulatory Compliance\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eManufactured under ISO 22000 food safety management standards; GMP-certified production facility; compliant with Singapore Food Agency (SFA) regulations; HSA Singapore health supplement notification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003eResearch Foundation\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eDeveloped from Asia's largest multi-ethnic microbiome reference database (AMILI BioCloud)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px; font-weight: bold;\"\u003ePackaging\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid #ddd; padding: 8px;\"\u003eSealed bottle with desiccant, tamper-evident closure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications and Key Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFunctional gastrointestinal symptom management including bloating, irregular bowel habits, abdominal discomfort, and functional dyspepsia in adults\u003c\/li\u003e\n\u003cli\u003ePost-antibiotic microbiome restoration and recolonisation following broad-spectrum antimicrobial therapy disrupting commensal gut bacteria\u003c\/li\u003e\n\u003cli\u003eGut barrier integrity reinforcement for individuals with increased intestinal permeability markers or chronic low-grade gastrointestinal inflammation\u003c\/li\u003e\n\u003cli\u003eTraveller's digestive health support for individuals exposed to novel microbial environments, unfamiliar dietary patterns, and water source changes\u003c\/li\u003e\n\u003cli\u003eRecommended formulation for individuals with AMILI Enhanced Gut Microbiome Test results indicating reduced microbial diversity, depleted Lactobacillus populations, or elevated pathobiont abundance\u003c\/li\u003e\n\u003cli\u003eAdjunctive digestive support for patients undergoing dietary interventions including elimination diets, low-FODMAP protocols, or therapeutic dietary transitions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhy does Formulation 4 contain a higher CFU count than other AMILI formulations?\u003c\/h3\u003e\n\u003cp\u003eFormulation 4 delivers 15 billion CFU per capsule compared to 9 billion (Formulation 1) and 12 billion (Formulations 2 and 3) because clinical trial evidence for digestive health endpoints consistently demonstrates dose-dependent responses. A meta-analysis published in the American Journal of Gastroenterology analysing probiotic interventions for functional gastrointestinal disorders found that formulations delivering 10 billion CFU or higher produced statistically significant improvements in global symptom scores, while lower doses showed inconsistent effects. The elevated count in Formulation 4 also compensates for organism attrition during gastrointestinal transit, ensuring therapeutic colony counts reach the colon.\u003c\/p\u003e\n\u003ch3\u003eWhat makes Limosilactobacillus reuteri the lead strain for digestive health?\u003c\/h3\u003e\n\u003cp\u003eL. reuteri is one of the most extensively characterised probiotic organisms in gastroenterology, with unique antimicrobial properties derived from its production of reuterin (3-hydroxypropionaldehyde), a broad-spectrum antimicrobial compound active against gram-positive and gram-negative pathogens. L. reuteri has also demonstrated the ability to modulate gastrointestinal motility through enteric nervous system interactions, reduce visceral pain perception, and strengthen tight junction protein expression in the intestinal epithelium. The World Gastroenterology Organisation (WGO) Global Guidelines list L. reuteri among recommended probiotic strains for multiple gastrointestinal indications.\u003c\/p\u003e\n\u003ch3\u003eCan Formulation 4 be used during antibiotic treatment?\u003c\/h3\u003e\n\u003cp\u003eProbiotic supplementation during antibiotic therapy is supported by clinical evidence, with a Cochrane systematic review demonstrating that concurrent probiotic use reduces antibiotic-associated diarrhoea incidence by approximately 42%. When taking Formulation 4 alongside antibiotics, a minimum 2-hour separation between antibiotic and probiotic doses is recommended to reduce direct antimicrobial exposure to the probiotic organisms. Supplementation should continue for at least 2-4 weeks after completing the antibiotic course to support microbiome recovery. Healthcare providers in Singapore should consider individual patient factors including antibiotic class, treatment duration, and patient history when advising on concurrent probiotic use.\u003c\/p\u003e\n\u003ch3\u003eHow does this formulation compare to generic digestive health probiotics available in pharmacies?\u003c\/h3\u003e\n\u003cp\u003eAMILI Formulation 4 differs from mass-market digestive probiotics in three key aspects: strain selection based on Asian population microbiome data rather than Western reference databases; delayed-release capsule technology ensuring colonic delivery rather than standard capsules where organisms are exposed to gastric acid; and a higher 15 billion CFU count reflecting clinical trial dosing protocols. Additionally, AMILI products are developed by a microbiome science company with proprietary metagenomic sequencing capabilities, and can be paired with the AMILI Enhanced Gut Microbiome Test for personalised baseline assessment and progress monitoring.\u003c\/p\u003e\n\u003ch3\u003eWhere can healthcare practitioners in Singapore procure AMILI Formulation 4?\u003c\/h3\u003e\n\u003cp\u003eAMILI Probiotics Formulation 4 is distributed in Singapore through EMIS (Essential Medical International Supplies Pte Ltd). Gastroenterology clinics, integrative medicine practices, functional medicine practitioners, and wellness centres can arrange institutional procurement with volume pricing. The product is classified as a health supplement under the Health Sciences Authority (HSA) Singapore regulatory framework. EMIS provides Certificates of Analysis, batch traceability documentation, and dedicated account management for healthcare institution partners requiring regulatory compliance documentation.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What are the benefits of Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience for digestive health?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience by Amili promotes gut microbiome diversity, supports digestive comfort, and strengthens the gut-immune axis. For individuals with digestive concerns such as IBS, bloating, or irregular bowel habits, targeted gut health supplementation may complement a balanced diet and lifestyle. Always consult a doctor or dietitian before starting supplements for digestive conditions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Who should take Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience may benefit adults seeking to support digestive health, those recovering from antibiotic use, individuals with irregular bowel habits, or those with conditions affecting gut microbiome balance. It is not a substitute for medical treatment. Consult your GP or gastroenterologist — available at SGH, NUH, Mount Elizabeth, and Raffles Hospital in Singapore — for personalised advice.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience for best results?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions on the Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience packaging or as directed by your healthcare provider. Consistency is key — most gut health supplements take 4–8 weeks of regular use to show measurable benefits. Store as directed on the label. Do not exceed the recommended daily dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Digestive Health Formulation 4 for Microbiota Balance and Gut Resilience is available at EMIS+ (emis.asia) with fast Singapore island-wide delivery. We carry a curated range of clinically-informed digestive health supplements. Visit emis.asia or contact our team for product recommendations.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Amili","offers":[{"title":"Default Title","offer_id":43232609435726,"sku":null,"price":90.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/Digestive_Health_Formulation_4_for_Microbiota_Balance_and_Gut_Resilience.png?v=1767712011"},{"product_id":"amili-probiotics-restore","title":"AMILI Probiotics Restore","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e AMILI Probiotics Restore is a Singapore-formulated multi-strain probiotic supplement designed to repopulate gut microbiota following antibiotic therapy, gastrointestinal disturbance, or travel-related dysbiosis. Each daily capsule delivers a clinically researched blend of Lactobacillus, Bifidobacterium and Saccharomyces strains. Formulated by AMILI, Southeast Asia's first precision microbiome company, the product is intended for adult use under healthcare practitioner guidance.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eAMILI Probiotics Restore is a multi-strain probiotic specifically positioned for the “rebuild” phase of gut microbiome care. The formulation pairs Lactobacillus and Bifidobacterium species with the yeast probiotic Saccharomyces boulardii, which has the longest evidence base for antibiotic-associated diarrhoea (AAD) prevention. Each capsule is delivered in a delayed-release vegetable shell to support viable colony delivery to the small and large intestine.\u003c\/p\u003e\n\u003cp\u003eAMILI is a Singapore-headquartered precision microbiome company operating Southeast Asia's first multi-ethnic gut microbiome bank. The Restore product is part of a graduated probiotic system used alongside the AMILI Enhanced Gut Microbiome Test and the AMILI Probiotic Formulations 1–4. It is commonly recommended by AMILI's clinical partners for patients completing antibiotic courses or recovering from acute gastrointestinal infection.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%;\" cellspacing=\"0\" cellpadding=\"6\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eManufacturer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAMILI Pte Ltd (Singapore)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eProduct line\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAMILI Probiotic System — Restore phase\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eVegetable capsule, delayed-release\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStrain composition\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMulti-strain: Lactobacillus acidophilus, Lactobacillus rhamnosus, Bifidobacterium longum, Bifidobacterium lactis, Saccharomyces boulardii\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eIndicated use\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAdjunct to antibiotic therapy; post-gastrointestinal infection recovery; travel-related dysbiosis support\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDosing\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 capsule daily with food, or per healthcare practitioner instruction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAllergens\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFree from gluten, dairy, soy, GMO and artificial colours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRegulatory\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHSA Singapore health supplement notification compliant; manufactured under ISO 22000 (food safety) and HACCP-certified facility; aligned with Codex Alimentarius probiotic guidelines and FAO\/WHO 2002 probiotic definition\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefrigerate at 2–8°C for maximum viable count; stable at ≤25°C for short-term transit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications \u0026amp; Key Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRestoration of commensal gut flora following oral or intravenous antibiotic therapy\u003c\/li\u003e\n\u003cli\u003eAdjunctive support for patients recovering from acute gastroenteritis or traveller's diarrhoea\u003c\/li\u003e\n\u003cli\u003eProphylaxis support for travel to regions of higher gastrointestinal infection risk\u003c\/li\u003e\n\u003cli\u003ePost-colonoscopy or post-bowel-prep microbiome reseeding under clinician guidance\u003c\/li\u003e\n\u003cli\u003eAdjunct to dietary fibre and prebiotic interventions in functional bowel symptom management\u003c\/li\u003e\n\u003cli\u003eGeneral gut microbiome maintenance for adults with intermittent dysbiosis symptoms\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: When is the optimal time to start AMILI Probiotics Restore relative to a course of antibiotics?\u003c\/strong\u003e\u003cbr\u003eA: Many gastroenterologists recommend starting probiotics on the same day as the antibiotic, taken at least 2–3 hours apart, and continuing for 1–2 weeks after the antibiotic course completes. AMILI's clinical guidance follows Cochrane and FAO\/WHO probiotic frameworks; defer to your prescribing clinician.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How does Restore differ from AMILI Probiotic Formulations 1–4?\u003c\/strong\u003e\u003cbr\u003eA: Restore is a broad multi-strain blend intended for general microbiome rebuilding. Formulations 1–4 are condition-targeted formulations (immune\/gut, complete metabolic, cognitive, and digestive resilience). Patients who have taken the AMILI Enhanced Gut Microbiome Test may receive a personalised recommendation among these.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Is the product suitable during pregnancy or breastfeeding?\u003c\/strong\u003e\u003cbr\u003eA: Lactobacillus and Bifidobacterium probiotics have a long safety record in healthy adults including pregnant individuals, but recommendations are individualised. Consult your obstetrician before initiating any new supplement.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How is product authenticity and CFU count maintained on shipment in Singapore?\u003c\/strong\u003e\u003cbr\u003eA: AMILI products are manufactured in HSA-notified, HACCP-certified facilities and shipped within Singapore using temperature-controlled fulfilment by EMIS Asia. Label CFU counts are guaranteed through end of shelf life when stored as directed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can it be taken alongside other probiotic or prebiotic products?\u003c\/strong\u003e\u003cbr\u003eA: Yes. Pairing a multi-strain probiotic with a fibre-rich prebiotic intake (or a separate prebiotic supplement) is considered a synbiotic approach and is widely supported in the clinical literature for gut microbiome diversity.\u003c\/p\u003e\n\u003ch2\u003eUse \u0026amp; Storage\u003c\/h2\u003e\n\u003cp\u003eAdults: take 1 capsule daily with a meal, or as directed by a qualified healthcare practitioner. Refrigerate after opening. Keep out of reach of children. Discontinue use and consult a clinician if adverse symptoms develop.\u003c\/p\u003e\n\u003cp\u003eEMIS Asia supplies AMILI products to Singapore clinics, integrative medicine practices, and authorised distributors with same-day local delivery and clinic account billing.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What are the benefits of Probiotics Restore for digestive health?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Probiotics Restore by Amili promotes gut microbiome diversity, supports digestive comfort, and strengthens the gut-immune axis. For individuals with digestive concerns such as IBS, bloating, or irregular bowel habits, targeted gut health supplementation may complement a balanced diet and lifestyle. Always consult a doctor or dietitian before starting supplements for digestive conditions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Who should take Probiotics Restore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Probiotics Restore may benefit adults seeking to support digestive health, those recovering from antibiotic use, individuals with irregular bowel habits, or those with conditions affecting gut microbiome balance. It is not a substitute for medical treatment. Consult your GP or gastroenterologist — available at SGH, NUH, Mount Elizabeth, and Raffles Hospital in Singapore — for personalised advice.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take Probiotics Restore for best results?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions on the Probiotics Restore packaging or as directed by your healthcare provider. Consistency is key — most gut health supplements take 4–8 weeks of regular use to show measurable benefits. Store as directed on the label. Do not exceed the recommended daily dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Probiotics Restore in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Probiotics Restore is available at EMIS+ (emis.asia) with fast Singapore island-wide delivery. 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